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Statistical analysisAnalysis followed a prespecified plan (see Cialis Generic Cost
supplementary file). We subjected each outcome to analysis of covariance within a multilevel (patients within practices) regression framework, following intention to treat principles and with the analyst (DR) blind to practice allocation. Although we powered the study to detect effects for separate conditions, we maximised power and minimised multiple testing in the analysis by testing for a treatment effect across all three condition groups combined, and for an interaction https://www.cialisbuy.co.uk between trial arm and condition group (controlled for the main effects of condition group). This analysis also controlled for baseline values of each outcome, design factors (practice list size, deprivation, and contractual type), and additional covariates.

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